Phetchaburi Railway Station is a 1st class station on the State Railway of Thailand (SRT) southern line. It opened in June 1903 during the reign of King Chulalongkorn, along with the first phase of the Southern Line from Thon Buri Station to Phetchaburi Station. At the time, the railway route was called "The Phetchaburi Railway Route". In 1911, the line was extended to Cha-am Station and then southwards to Sungai Kolok and Padang Besar during King Vajiravudh's reign.

The train services operating on this route are:
• Special Express 43/44 Bangkok-Surat Thani-Bangkok
• Special Express 35/36 Bangkok-Butterworth-Bangkok
• Special Express 37/38 Bangkok-Sungai Kolok-Bangkok
• Ordinary 261/262 Bangkok-Hua Hin-Bangkok
• Rapid 171/172 Bangkok-Sungai Kolok-Bangkok
• Rapid 169/170 Bangkok-Yala-Bangkok
• Express 83/84 Bangkok-Trang-Bangkok
• Rapid 173/174 Bangkok-Nakhon Si Thammarat-Bangkok
• Rapid 167/168 Bangkok-Kantang-Bangkok
• Express 85/86 Bangkok-Nakhon Si Thammarat-Bangkok
• Special Express 39/40 Bangkok-Surat Thani-Bangkok
• Special Express 41/42 Bangkok-Yala-Bangkok
• Ordinary 251/252 Bang Sue Junction-Prachuap Khiri Khan-Bang Sue Junction
• Ordinary 254/255 Lang Suan-Thon Buri-Lang Suan
• Rapid 177/178 Thon Buri-Lang Suan-Thon Buri